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Written by: FormBlends Medical Team | Last reviewed: May 29, 2026 | Sources: PubMed, peer-reviewed pharmacology journals, FDA databases

42 SofroniewM

An inflammatory process is implicated in the pathophysiology of MDD

Huyard C

Converting tanshinone IIA into its sodium sulfonate form (sodium tanshinone IIA sulfonate, STS) greatly increases polarity and bioavailability, and indeed STS is used interchangeably with tanshinone IIA in studies and has been approved in China as an injectable drug (Shao et al., 2024